Bioinformatics and computational biology in drug discovery and development /

Bioinformatics and computational biology in drug discovery and development /

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Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previous...

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Bibliographic Details
Corporate Author: Cambridge University Press
Other Authors: Loging, William T. (Editor)
Format: Book
Language:English
Published: Cambridge : Cambridge University Press, 2016
Cambridge, United Kingdom : 2016
Subjects:
Bioinformatics
Computational biology
Drug development
Drugs > Design > Data processing
Drugs > Design
Drug Discovery > methods
Biomarkers, Pharmacological
Computational Biology > methods
Data Mining > methods
Table of Contents:
  • Machine generated contents note: Foreword; Preface: the future of drug discovery and health care / Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) / William T. Loging; 2. Computational approaches to drug target identification / Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining / Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development / Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery / William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process / Ke Xu; 7. Information visualization - important IT considerations / Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages / William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning / Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches / Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources / Yirong Wang and William T. Loging; Index
  • Machine generated contents note: Foreword; Preface: the future of drug discovery and health care / Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) / William T. Loging; 2. Computational approaches to drug target identification / Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining / Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development / Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery / William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process / Ke Xu; 7. Information visualization
  • important IT considerations / Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages / William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning / Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches / Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources / Yirong Wang and William T. Loging; Index

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