Table of Contents:
  • Contents: The immune pathogenesis of type 1 diabetes
  • Genetic associations with type 1 diabetes
  • The role of cytotoxic CD8 T cells
  • The role of helper CD4 T cells, and the regulatory subset of CD4 T cells
  • Autoantibodies and autoreactive B cells
  • Environmental influences
  • Implications for immune-based therapy?