Cytokine knockouts /

Carrying on the high standards of the much praised first edition (Durum and Muegge, Cytokine Knockouts, 1998), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology. Comp...

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Bibliographic Details
Other Authors: Fantuzzi, Giamila
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2003], ©2003
Totowa, N.J. : c2003
Totowa, N.J. : [2003]
Edition:2nd ed
Series:Contemporary immunology
Contemporary immunology
Subjects:
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245 0 0 |a Cytokine knockouts /  |c edited by Giamila Fantuzzi ; foreword by Scott K. Durum 
250 |a 2nd ed 
250 |a 2nd ed. /  |b edited by Giamila Fantuzzi ; foreword by Scott K. Durum 
250 |a Second edition 
260 |a Totowa, N.J. :  |b Humana Press,  |c [2003], ©2003 
260 |a Totowa, N.J. :  |b Humana Press,  |c c2003 
264 1 |a Totowa, N.J. :  |b Humana Press,  |c [2003] 
264 4 |c ©2003 
300 |a xix, 471 p. :  |b ill. ;  |c 26 cm 
300 |a xix, 471 pages :  |b illustrations ;  |c 26 cm 
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440 0 |a Contemporary immunology 
490 1 |a Contemporary immunology 
500 |a This WorldCat-derived record is shareable under Open Data Commons ODC-BY, with attribution to OCLC  |5 CTY 
504 |a Includes bibliographical references and index 
505 0 0 |g 1  |t Cytokine Knockouts in Inflammation /  |r Pietro Ghezzi --   |g 2.  |t The Use of Cytokine Knockouts to Study Host Defense Against Infection /  |r Charles A. Dinarello --   |g 3.  |t The Use of Cytokine Knockouts in Animal Models of Autoimmune Disease /  |r Alfons Billiau, Hubertine Heremans and Patrick Matthys --   |g 4.  |t The Use of Cytokine Knockout Mice in Cancer Research /  |r Robert H. Wiltrout, Jon M. Wigginton and William J. Murphy --   |g 5.  |t The Use of Cytokine Knockout Mice in Neuroimmunology /  |r Giamal N. Luheshi, Emmanuel Pinteaux and Herve Boutin --   |g 6.  |t The Role of IL-1 in the Immune System /  |r Susumu Nakae, Reiko Horai, Yutaka Komiyama, Aya Nambu, Masahide Asano, Akio Nakane and Yoichiro Iwakura --   |g 7.  |t IL-1 Receptor Antagonist-Deficient Mice /  |r Martin J. H. Nicklin and Joanna Shepherd --   |g 8.  |t A Unique Role for IL-2 in Self-Tolerance /  |r Thomas Hunig and Anneliese Schimpl --   |g 9.  |t Molecular Basis for Binding Multiple Cytokines by [gamma]c: Implications for X-SCID and Impaired [gamma]c-Dependent Cytokine Receptor Function /  |r Ferenc Olosz and Thomas R. Malek --   |g 10.  |t G-CSF, GM-CSF, and IL-3 Knockout Mice /  |r Thomas Enzler and Glenn Dranoff --   |g 11.  |t IL-4 Knockout Mice /  |r Pascale Kropf and Ingrid Muller --   |g 12.  |t Role of IL-5 in Immune and Pathological Responses in the Mouse /  |r Paul S. Foster and Simon P. Hogan --   |g 13.  |t IL-6 Knockout Mice /  |r Valeria Poli and Diego Maritano --   |g 14.  |t IL-10 and IL-2 Knockout Mice: Effect on Intestinal Inflammation /  |r Karen L. Madsen and Humberto Jijon --   |g 15.  |t IL-12-Deficient Mice /  |r Luciano Adorini --   |g 16.  |t IL-13 and Double IL-4/IL-13 Knockout Mice /  |r Duncan R. Hewett and Andrew N. J. McKenzie --   |g 17.  |t IL-15: Insights from Characterizing IL-15-Deficient Mice /  |r Pallavur V. Sivakumar, Sandra N. Brown, Ananda W. Goldrath, Anne Renee Van der Vuurst de Vries, Joanne L. Viney and Mary K. Kennedy --   |g 18.  |t IL-18 and IL-18 Receptor Knockout Mice /  |r Hiroko Tsutsui, Tomohiro Yoshimoto, Haruki Okamura, Shizuo Akira and Kenji Nakanishi --   |g 19.  |t Mice Knockouts for Chemokines and Chemokine Receptors /  |r Jane M. Schuh, Steven L. Kunkel and Cory M. Hogaboam --   |g 20.  |t IFN-[gamma] and IFN-[gamma] Receptor Knockout Mice /  |r Dyana Dalton --   |g 21.  |t Macrophage Migration Inhibitory Factor (MIF)-Deficient Mice /  |r Gunter Fingerle-Rowson, Abhay R. Satoskar and Richard Bucala --   |g 22.  |t Osteopontin, a Surprisingly Flexible Cytokine: Functions Revealed from Osteopontin Knockout Mice /  |r Susan R. Rittling, Anthony W. O'Regan and Jeffrey S. Berman --   |g 23.  |t RANKL, RANK, and OPG /  |r Young-Yun Kong and Josef M. Penninger --   |g 24.  |t Targeting the TGF-[beta] Pathway In Vivo: Defining Complex Roles for TGF-[beta] Signaling in Immune Function, Wound Healing, and Carcinogenesis /  |r Lawrence Wolfraim, Mizuko Mamura, Anita Roberts and John J. Letterio --   |g 25.  |t Physiologic Roles of Members of the TNF and TNF Receptor Families as Revealed by Knockout Models /  |r Sergei A. Nedospasov, Sergei I. Grivennikov and Dmitry V. Kuprash. 
505 0 0 |g 1  |t Cytokine Knockouts in Inflammation /  |r Pietro Ghezzi --  |g 2.  |t The Use of Cytokine Knockouts to Study Host Defense Against Infection /  |r Charles A. Dinarello --  |g 3.  |t The Use of Cytokine Knockouts in Animal Models of Autoimmune Disease /  |r Alfons Billiau, Hubertine Heremans and Patrick Matthys --  |g 4.  |t The Use of Cytokine Knockout Mice in Cancer Research /  |r Robert H. Wiltrout, Jon M. Wigginton and William J. Murphy --  |g 5.  |t The Use of Cytokine Knockout Mice in Neuroimmunology /  |r Giamal N. Luheshi, Emmanuel Pinteaux and Herve Boutin --  |g 6.  |t The Role of IL-1 in the Immune System /  |r Susumu Nakae, Reiko Horai, Yutaka Komiyama, Aya Nambu, Masahide Asano, Akio Nakane and Yoichiro Iwakura --  |g 7.  |t IL-1 Receptor Antagonist-Deficient Mice /  |r Martin J. H. Nicklin and Joanna Shepherd --  |g 8.  |t A Unique Role for IL-2 in Self-Tolerance /  |r Thomas Hunig and Anneliese Schimpl --  |g 9.  |t Molecular Basis for Binding Multiple Cytokines by [gamma]c: Implications for X-SCID and Impaired [gamma]c-Dependent Cytokine Receptor Function /  |r Ferenc Olosz and Thomas R. Malek --  |g 10.  |t G-CSF, GM-CSF, and IL-3 Knockout Mice /  |r Thomas Enzler and Glenn Dranoff --  |g 11.  |t IL-4 Knockout Mice /  |r Pascale Kropf and Ingrid Muller --  |g 12.  |t Role of IL-5 in Immune and Pathological Responses in the Mouse /  |r Paul S. Foster and Simon P. Hogan --  |g 13.  |t IL-6 Knockout Mice /  |r Valeria Poli and Diego Maritano --  |g 14.  |t IL-10 and IL-2 Knockout Mice: Effect on Intestinal Inflammation /  |r Karen L. Madsen and Humberto Jijon --  |g 15.  |t IL-12-Deficient Mice /  |r Luciano Adorini --  |g 16.  |t IL-13 and Double IL-4/IL-13 Knockout Mice /  |r Duncan R. Hewett and Andrew N. J. McKenzie --  |g 17.  |t IL-15: Insights from Characterizing IL-15-Deficient Mice /  |r Pallavur V. Sivakumar, Sandra N. Brown, Ananda W. Goldrath, Anne Renee Van der Vuurst de Vries, Joanne L. Viney and Mary K. Kennedy --  |g 18.  |t IL-18 and IL-18 Receptor Knockout Mice /  |r Hiroko Tsutsui, Tomohiro Yoshimoto, Haruki Okamura, Shizuo Akira and Kenji Nakanishi --  |g 19.  |t Mice Knockouts for Chemokines and Chemokine Receptors /  |r Jane M. Schuh, Steven L. Kunkel and Cory M. Hogaboam --  |g 20.  |t IFN-[gamma] and IFN-[gamma] Receptor Knockout Mice /  |r Dyana Dalton --  |g 21.  |t Macrophage Migration Inhibitory Factor (MIF)-Deficient Mice /  |r Gunter Fingerle-Rowson, Abhay R. Satoskar and Richard Bucala --  |g 22.  |t Osteopontin, a Surprisingly Flexible Cytokine: Functions Revealed from Osteopontin Knockout Mice /  |r Susan R. Rittling, Anthony W. O'Regan and Jeffrey S. Berman --  |g 23.  |t RANKL, RANK, and OPG /  |r Young-Yun Kong and Josef M. Penninger --  |g 24.  |t Targeting the TGF-[beta] Pathway In Vivo: Defining Complex Roles for TGF-[beta] Signaling in Immune Function, Wound Healing, and Carcinogenesis /  |r Lawrence Wolfraim, Mizuko Mamura, Anita Roberts and John J. Letterio --  |g 25.  |t Physiologic Roles of Members of the TNF and TNF Receptor Families as Revealed by Knockout Models /  |r Sergei A. Nedospasov, Sergei I. Grivennikov and Dmitry V. Kuprash. 
505 0 0 |g 1  |t Cytokine Knockouts in Inflammation /  |r Pietro Ghezzi --  |g 2.  |t The Use of Cytokine Knockouts to Study Host Defense Against Infection /  |r Charles A. Dinarello --  |g 3.  |t The Use of Cytokine Knockouts in Animal Models of Autoimmune Disease /  |r Alfons Billiau, Hubertine Heremans and Patrick Matthys --  |g 4.  |t The Use of Cytokine Knockout Mice in Cancer Research /  |r Robert H. Wiltrout, Jon M. Wigginton and William J. Murphy --  |g 5.  |t The Use of Cytokine Knockout Mice in Neuroimmunology /  |r Giamal N. Luheshi, Emmanuel Pinteaux and Herve Boutin --  |g 6.  |t The Role of IL-1 in the Immune System /  |r Susumu Nakae, Reiko Horai, Yutaka Komiyama, Aya Nambu, Masahide Asano, Akio Nakane and Yoichiro Iwakura --  |g 7.  |t IL-1 Receptor Antagonist-Deficient Mice /  |r Martin J. H. Nicklin and Joanna Shepherd --  |g 8.  |t A Unique Role for IL-2 in Self-Tolerance /  |r Thomas Hunig and Anneliese Schimpl --  |g 9.  |t Molecular Basis for Binding Multiple Cytokines by [gamma]c: Implications for X-SCID and Impaired [gamma]c-Dependent Cytokine Receptor Function /  |r Ferenc Olosz and Thomas R. Malek --  |g 10.  |t G-CSF, GM-CSF, and IL-3 Knockout Mice /  |r Thomas Enzler and Glenn Dranoff --  |g 11.  |t IL-4 Knockout Mice /  |r Pascale Kropf and Ingrid Muller --  |g 12.  |t Role of IL-5 in Immune and Pathological Responses in the Mouse /  |r Paul S. Foster and Simon P. Hogan --  |g 13.  |t IL-6 Knockout Mice /  |r Valeria Poli and Diego Maritano --  |g 14.  |t IL-10 and IL-2 Knockout Mice: Effect on Intestinal Inflammation /  |r Karen L. Madsen and Humberto Jijon --  |g 15.  |t IL-12-Deficient Mice /  |r Luciano Adorini --  |g 16.  |t IL-13 and Double IL-4/IL-13 Knockout Mice /  |r Duncan R. Hewett and Andrew N. J. McKenzie --  |g 17.  |t IL-15: Insights from Characterizing IL-15-Deficient Mice /  |r Pallavur V. Sivakumar, Sandra N. Brown, Ananda W. Goldrath, Anne Renee Van der Vuurst de Vries, Joanne L. Viney and Mary K. Kennedy --  |g 18.  |t IL-18 and IL-18 Receptor Knockout Mice /  |r Hiroko Tsutsui, Tomohiro Yoshimoto, Haruki Okamura, Shizuo Akira and Kenji Nakanishi -- 
505 8 0 |g 19  |t Mice Knockouts for Chemokines and Chemokine Receptors /  |r Jane M. Schuh, Steven L. Kunkel and Cory M. Hogaboam --  |g 20.  |t IFN-[gamma] and IFN-[gamma] Receptor Knockout Mice /  |r Dyana Dalton --  |g 21.  |t Macrophage Migration Inhibitory Factor (MIF)-Deficient Mice /  |r Gunter Fingerle-Rowson, Abhay R. Satoskar and Richard Bucala --  |g 22.  |t Osteopontin, a Surprisingly Flexible Cytokine: Functions Revealed from Osteopontin Knockout Mice /  |r Susan R. Rittling, Anthony W. O'Regan and Jeffrey S. Berman --  |g 23.  |t RANKL, RANK, and OPG /  |r Young-Yun Kong and Josef M. Penninger --  |g 24.  |t Targeting the TGF-[beta] Pathway In Vivo: Defining Complex Roles for TGF-[beta] Signaling in Immune Function, Wound Healing, and Carcinogenesis /  |r Lawrence Wolfraim, Mizuko Mamura, Anita Roberts and John J. Letterio --  |g 25.  |t Physiologic Roles of Members of the TNF and TNF Receptor Families as Revealed by Knockout Models /  |r Sergei A. Nedospasov, Sergei I. Grivennikov and Dmitry V. Kuprash. 
520 |a Carrying on the high standards of the much praised first edition (Durum and Muegge, Cytokine Knockouts, 1998), Giamila Fantuzzi and a panel of experts have generated completely new chapters to reflect the use of many novel mouse strains and the hundreds of recent studies on cytokine physiology. Comprehensive reviews of the numerous often-surprising results obtained using cytokine knockout mice are provided, along with much important information about cytokine biology and physiology. For those not familiar with cytokine research, the authors present a critical discussion of the advantages and disadvantages of using cytokine knockout mice in various fields of research 
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