Microbiological quality assurance : a guide towards relevance and reproducibility of inocula /

"Microbiological Quality Assurance: A Guide Towards Relevance and Reproducibility of Inocula sheds light on the difficulties of obtaining results in the test tube that will be reproducible and relevant for a wide variety of tests. This book explores the current state of research in this area an...

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Bibliographic Details
Other Authors: Brown, Michael R. W (Michael Robert Withington), 1931- (Editor), Gilbert, Peter, 1951- (Editor)
Format: Book
Language:English
Published: Boca Raton, FL : CRC Press, 2018
Boca Raton, Fla. : 2018
Series:CRC revivals
Subjects:
Table of Contents:
  • Cover; Half Title; Title; Copyright; Preface; The Editors; Contributors; Table Of Contents; GROWTH CONDITIONS; Chapter 1.1: Influence of the Environment on the Properties of Vegetative Microorganisms: An Overview; Introduction; Phenotypic Flexibility; Growth Rate and Nutient Deprivation; Growth as Adherent Biofilms; Solid or Liquid Culture for Conventional Susceptibility Testing; Conclusions; References; Chapter 1.2: Definition of Phenotype in Batch Culture; Introduction; Specific Nutrient Depletion in Batch Culture; Defined Nutrient-Depleted Media; An Empirical Approach
  • part Growth Conditions
  • chapter 1.1 Influence of the Environment on the Properties of Vegetative Microorganisms: An Overview / Michael R. W. Brown
  • chapter 1.2 Definition of Phenotype in Batch Culture / Michael R. W. Brown
  • chapter 1.3 Changes in Bacterial Cell Properties in Going from Exponential Growth to Stationary Phase / Maria M. Zambrano
  • chapter 1.4 Continuous Culture of Microorganisms in Liquid Media: Effects of Growth Rate and Nutrient Limitation / Peter Gilbert
  • chapter 1.5 The Influence of Nutrient Environment During Vegetative Growth on the Properties of Bacterial Endospores / Peter Gilbert
  • chapter 1.6 Influence of the Environment on the Properties of Microorganisms Grown in Association with Surfaces / Peter Gilbert
  • chapter 1.7 Sources of Biological Variation and Lack of Inoculum Reproducibility: A Summary / Michael R.W. Brown
  • part Post-Growth Conditions
  • chapter 2.1 The Preservation of Inocula / Gerald D.J. Adams
  • chapter 2.2 Influence of Post-Growth Procedures on the Properties of Microorganisms
  • (Out of the Test Tube into the Frying Pan) / Peter Gilbert
  • part Applications
  • chapter 3.1 Factors Affecting the Reproducibility and Predictivity of Performance Tests / Peter Gilbert
  • chapter 3.2 Preservative Efficacy Testing in the Pharmaceutical Industries / Rosamund M. Baird
  • chapter 3.3 Preservation Efficacy Testing in the Cosmetics and Toiletries Industries / Brian F. Perry
  • chapter 3.4 Reproducibility and Predictivity of Disinfection and Biocide Tests / Sally F. Bloomfield
  • chapter 3.5 Reproducibility and Performance of Endospores as Biological Indicators / Norman Hodges
  • chapter 3.6 Development and Production of Vaccines / Andrew Robinson
  • chapter 3.7 Screening for Novel Antimicrobial Activity/Compounds in the Pharmaceutical Industry / Peter Gilbert
  • chapter 3.8 Screening for Novel Compounds/Activity in the Environmental Protection Industries / Hilary M. Lappin-Scott
  • chapter 3.9 Antimicrobial Susceptibility Testing Within the Clinic / Kenneth S. Thomson
  • A Quantitative ApproachUSP Preservative Test Organisms; References; Chapter 1.3: Changes in Bacterial Cell Properties in Going from Exponential Growth to Stationary Phase; Introduction; Changes that Result from Starvation; Regulation of Gene Expression in Stationary Phase; Population Changes during Starvation; Acknowledgments; References; Chapter 1.4: Continuous Culture of Microorganisms in Liquid Media: Effects of Growth Rate and Nutrient Limitation; Introduction; Continuous Culture: Theoretical Considerations; Carbon Limitation; Magnesium and Iron Limitation; Oxygen Limitation; Turbidostats
  • Chapter 1.6: Influence of the Environment on the Properties of Microorganisms Grown in Association with SurfacesIntroduction; Surface Colonization and Growth; Resistance Properties of Bacterial Biofilms; Influence of Surface Attachment and Growth upon Microbial Activity; Role of the Glycocalyx; The Glycocalyx as a Moderator of Drug/Biocide Resistance; Attachment-Specific Physiologies; Quorum Sensing Transcriptional Activation; In Vitro Models of Biofilms; Closed Growth Models; Solid:Air Interfaces; Solid: Liquid Interfaces; Open Growth Models (Non-Steady-State); Chemostat-Based Models
  • Continuous Culture: Practical ConsiderationsCulture Homogeneity; Foaming; Floccules; Biofilms; Continuous Culture Fermenter Design; Modulation of Antimicrobial Susceptibility in Continuous Culture; Susceptibility Towards Chemical Biocides; Susceptibility Towards Antibiotics; References; Chapter 1.5: The Influence of Nutrient Environment During Vegetative Growth on the Properties of Bacterial Endospores; Introduction; Sporulation Medium and Definition of Spore Phenotype; Sporulation Temperature; Growth and Sporulation at Various pH; Culture Age Prior to Harvesting; References
  • The Robbins DeviceAnnular Reactor; Open Growth Models (Steady-State); Constant Thickness Biofilms; Perfused Biofilms; Conclusions; References; Chapter 1.7: Sources of Biological Variation and Lack of Inoculum Reproducibility: A Summary; Culture Origins; Growth Conditions of the Inoculum; Dormancy; Post-Growth Handling Procedures; Procedureffest Conditions; POST -GROWTH CONDITIONS; Chapter 2.1: The Preservation of Inocula; Introduction; Reproducibility; Biochemical Properties; Genetic Stability; Preservation by Cooling; Behavior of Solutes During Freezing; Rates of Cooling