Core concepts in acute kidney injury /
This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes...
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| Other Authors: | , , , , |
| Format: | Book |
| Language: | English |
| Published: |
New York, NY :
Springer US : Imprint: Springer,
2018
New York, NY, U.S.A. : Springer, [2018] |
| Subjects: |
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| 245 | 0 | 0 | |a Core concepts in acute kidney injury / |c Sushrut S. Waikar, Patrick T. Murray, Ajay K. Singh, editors |
| 264 | 1 | |a New York, NY : |b Springer US : |b Imprint: Springer, |c 2018 | |
| 264 | 1 | |a New York, NY, U.S.A. : |b Springer, |c [2018] | |
| 300 | |a 1 online resource (XII, 373 pages) : |b 73 illustrations, 57 illustrations in color | ||
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| 336 | |a text |b txt |2 rdacontent | ||
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| 504 | |a Includes bibliographical references and index | ||
| 505 | 0 | |a Intro; Preface; Contents; Contributors; Part I: Epidemiology and Diagnosis; 1: Epidemiology, Incidence, Risk Factors, and Outcomes of Acute Kidney Injury; 1.1 Background; 1.2 Epidemiology; 1.3 Risk Factors for the Development of AKI; 1.4 CKD, CVD and ESRD as Possible Outcomes After an Episode of AKI; 1.5 Risk Factors for Poor Outcomes Following AKI; 1.6 Potential Pathogenetic Mechanisms for AKI: CKD Transition; References; 2: Definition and Classification of Acute Kidney Injury; 2.1 Diagnosis and Staging of AKI; 2.2 RIFLE Criteria | |
| 505 | 0 | |a Part I Epidemiology and Diagnosis -- Chapter 1 Epidemiology, Incidence, Risk Factors, and Outcomes of Acute Kidney Injury -- Chapter 2 Definition and Classification of Acute Kidney Injury -- Chapter 3 Diagnostic Approach: Differential Diagnosis, Physical Exam, Lab Tests, Imaging and Novel Biomarkers -- Part II Pathophysiology -- Chapter 4 Overview of Pathophysiology of Acute Kidney Injury: Human Evidence, Mechanisms, Pathological Correlations and Biomarkers, and Animal Models -- Chapter 5 Tubular Physiology in Acute Kidney Injury: Cell Signaling, Injury, and Inflammation -- Part III Clinical Syndromes -- Chapter 6 Contrast-Associated Acute Kidney Injury -- Chapter 7 Acute Kidney Injury and Liver Disease: Incidence, Pathophysiology, Prevention/Treatment, Outcomes -- Chapter 8 Acute Kidney Injury and Cancer: Incidence, Pathophysiology, Prevention/Treatment, Outcomes -- Chapter 9 Drug-Induced Acute Kidney Injury -- Chapter 10 Sepsis and Acute Kidney Injury: Epidemiology, Pathophysiology, Diagnosis, and Management -- Chapter 11 Acute Kidney Failure and Minimal Change Disease -- Chapter 12 Core Concepts: Post-Cardiac Surgery Acute Kidney Injury -- Chapter 13 Rare and Overlooked Causes of Acute Kidney Injury -- Chapter 14 Acute Kidney Injury in Tropics: Epidemiology, Presentation, Etiology, Specific Diseases, and Treatment -- Chapter 15 Pediatric Acute Kidney Injury: Diagnosis, Epidemiology, and Treatment -- Chapter 16 Post-Renal Acute Kidney Injury: Epidemiology, Presentation, Pathophysiology, Diagnosis, and Management -- Chaper 17 Cardiorenal Acute Kidney Injury: Epidemiology, Presentation, Causes, Pathophysiology and Treatment -- Chapter 18 Perioperative (non-cardiac) Acute Kidney Injury: Epidemiology, Pathophysiology, Prevention, and Treatment -- Part IV Management -- Chapter 19 Non-Dialytic Management of Acute Kidney Injury -- Chapter 20 Diuretics in Acute Kidney Injury -- Chapter 21 Emerging Therapies for Acute Kidney Injury: What's on the Horizon? -- Chapter 22 Dialytic Therapy of Acute Kidney Injury -- Chapter 23 Drug Dosing in Acute Kidney Injury | |
| 505 | 8 | |a 2.3 Acute Kidney Injury Network (AKIN) Definition and Staging Criteria2.4 Kidney Disease: Improving Global Outcomes (KDIGO) Classification; 2.5 AKI Definition and Staging in Pediatric Patients; 2.6 Validation of AKI Definitions; 2.7 Limitations of the Current Definitions and Staging Criteria; 2.8 Use of AKI Definitions in Epidemiology and Clinical Research; 2.9 Utility of AKI Definitions and Staging in Clinical Care; References; 3: Diagnostic Approach: Differential Diagnosis, Physical Exam, Lab Tests, Imaging, and Novel Biomarkers; 3.1 Differential Diagnosis | |
| 505 | 8 | |a 3.1.1 Rethinking the Differential Diagnosis of AKI3.2 Physical Exam; 3.3 Lab Tests; 3.3.1 Blood Tests; 3.3.2 Urinary Test; 3.4 Imaging; 3.5 Novel Biomarkers; References; Part II: Pathophysiology; 4: Overview of Pathophysiology of Acute Kidney Injury: Human Evidence, Mechanisms, Pathological Correlations and Biomarkers and Animal Models; 4.1 Introduction: Evidence of the Human Significance of Acute Kidney Injury; 4.2 Defining Acute Kidney Injury; 4.2.1 Traditional Acute Kidney Injury Descriptors; 4.2.2 Functional Descriptors: Serum Creatinine, SCr, and Oliguria | |
| 505 | 8 | |a 4.3 Aetiology of Acute Kidney Injury4.4 Pathophysiology of Acute Kidney Injury; 4.4.1 Tubular Injury and Linked Biomarkers; 4.4.2 Apoptosis and Mitochondrial Associations; 4.4.3 Necrosis and Necroptosis; 4.4.4 Autophagic Cell Death; 4.4.5 Relationship Between Tubular Damage and Reduced GFR; 4.4.6 Endothelial and Vascular Injury; 4.4.7 Inflammation and the Immune Response; 4.5 Biomarkers; 4.5.1 Damage Biomarkers for Early Diagnosis of AKI; 4.6 Novel Roles for Damage Biomarkers in Acute Kidney Injury; 4.6.1 Differential Diagnosis; 4.6.2 Biomonitoring Treatment Success or Failure | |
| 505 | 8 | |a 4.7 Recovery and Renal Reserve4.7.1 Maladaptive Healing and Chronic Kidney Disease; 4.8 Animal Models; References; 5: Tubular Physiology in Acute Kidney Injury: Cell Signalling, Injury and Inflammation; 5.1 Introduction; 5.2 Cell Polarity in AKI; 5.2.1 Acute Injury; 5.3 Cell Signalling in AKI; 5.3.1 Arachidonic Acid Metabolites; 5.3.2 Adenosine Triphosphate (ATP); 5.3.3 Nitric Oxide; 5.3.4 Dopamine; 5.3.5 Angiotensin II; 5.3.6 Bradykinin; 5.4 Heme Oxygenase-1; 5.4.1 Heme Oxygenase and the Kidney; 5.4.2 Renal Blood Flow and the Microcirculation | |
| 506 | |a Restricted for use by site license | ||
| 520 | |a This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI | ||
| 588 | |a Online resource; title from PDF title page (EBSCO, viewed September 19, 2018) | ||
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