Stuart Kauffman
Stuart Alan Kauffman (born September 28, 1939) is an American medical doctor, theoretical biologist, and complex systems researcher who studies the origin of life on Earth. He was a professor at the University of Chicago, University of Pennsylvania, and University of Calgary. He is currently emeritus professor of biochemistry at the University of Pennsylvania and affiliate faculty at the Institute for Systems Biology. He has a number of awards including a MacArthur Fellowship and a Wiener Medal.He is best known for arguing that the complexity of biological systems and organisms might result as much from self-organization and far-from-equilibrium dynamics as from Darwinian natural selection, as discussed in his book ''Origins of Order'' (1993). In 1967 and 1969 he used random Boolean networks to investigate generic self-organizing properties of gene regulatory networks, proposing that cell types are dynamical attractors in gene regulatory networks and that cell differentiation can be understood as transitions between attractors. Recent evidence suggests that cell types in humans and other organisms are attractors. In 1971 he suggested that a zygote may not be able to access all the cell type attractors in its gene regulatory network during development and that some of the developmentally inaccessible cell types might be cancer cell types. This suggested the possibility of "cancer differentiation therapy". He also proposed the self-organized emergence of collectively autocatalytic sets of polymers, specifically peptides, for the origin of molecular reproduction, which have found experimental support. Provided by Wikipedia
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2by Kauffman, Stuart A, Kauffman, Stuart A, Kauffman, Stuart A., Kauffman, Stuart A., Kauffman, Stuart A.
Published 2016
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9by Kauffman, Stuart A.
Published 2023
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10by Kauffman, Stuart A
Published 2008
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12by Kauffman, Stuart A.
Published 1993
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13by Kauffman, Stuart A
Published 2002
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14by Kauffman, Stuart A
Published 1995
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15by Kauffman, Stuart A.
Published 2000
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16by Kauffman, Stuart A
Published 2008
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17Ke xue xin ling yu de tan suo = Investigation /科学新领域的探索 = Investigation /by Kauffman, Stuart A
Published 2004
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18Jiko soshikika to shinka no ronri : uchū o tsuranuku fukuzatsukei no hōsoku /自己組織化と進化の論理 : 宇宙を貫く複雑系の法則 /by Kauffman, Stuart A
Published 1999
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19by Kauffman, Stuart A.
Published 2016
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20by Kauffman, Stuart A.
Published 2016
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