T cell immunosurveillance in pancreatic ductal adenocarcinoma /
Here, using a genetic mouse model of spontaneous pancreatic carcinoma that features an immunosuppressive microenvironment and few non-synonymous mutations, we report that the natural history of such cancers is T cell-independent. Furthermore, tumor escape from T cell surveillance is not required for...
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Other Authors: | , , , |
Format: | Thesis Book |
Language: | English |
Published: |
[Philadelphia, Pennsylvania]: Ann Arbor :
University of Pennsylvania ; ProQuest Dissertations & Theses,
2015
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Subjects: |