T cell immunosurveillance in pancreatic ductal adenocarcinoma /

Here, using a genetic mouse model of spontaneous pancreatic carcinoma that features an immunosuppressive microenvironment and few non-synonymous mutations, we report that the natural history of such cancers is T cell-independent. Furthermore, tumor escape from T cell surveillance is not required for...

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Bibliographic Details
Main Author: Evans, Rebecca A. (Author)
Other Authors: Conejo-Garcia, Jose R. (degree committee member), Keith, Brian D. (degree committee member), Mason, Nicola J. (degree committee member), Stanger, Benjamin Z. (degree committee member)
Format: Thesis Book
Language:English
Published: [Philadelphia, Pennsylvania]: Ann Arbor : University of Pennsylvania ; ProQuest Dissertations & Theses, 2015
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